OMEGAZONE OZ-EX1 laser speckle blood flow imager for mice & rats. 3 imaging modes, polarization anti-artifact design, split LSI/LIA software for real-time & post-analysis, ideal for neuroscience & preclinical vascular research.

Application

Cerebral cortex blood flow monitoring for rodent MCAO stroke ischemia/reperfusion models Limb skin, flap graft tissue perfusion & survival evaluation Spinal cord and peripheral nerve microcirculation research Mucosa, gingival tissue blood flow measurement for dental & allergy studies Vasodilation, vasoconstriction and ischemic tissue perfusion dynamic tracking Environmental physiology, pharmacology and vascular drug efficacy testing Preclinical in vivo microcirculation & angiogenesis research Dermatology, inflammation and hypersensitivity animal model analysis University neuroscience, biomedical engineering and pharmaceutical laboratory research

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DESCRIPTION
PARAMETERS
FEATURE

Product Description

The OMEGAZONE OZ-EX1 is a compact 2D Laser Speckle Blood Flow Imager specially developed for non-invasive, continuous, high-speed and high-resolution tissue blood flow measurement on small laboratory animals including mice, rats and other rodents. Built as a miniaturized upgraded version of the classic OZ-2 model, it integrates miniaturized laser unit and CMOS camera to fit limited lab bench and hood space, powered entirely via computer USB without extra external power adapters.

Working on laser speckle contrast imaging (LSCI) principle with built-in polarization filter, the system eliminates surface reflection artifacts to deliver stable, distortion-free perfusion mapping. All tissue points are measured simultaneously without time lag, enabling accurate comparison of blood flow correlation and dynamic perfusion changes across the full field of view. By swapping interchangeable lenses, users flexibly adjust the imaging area ranging from 8×6 mm up to 108×80 mm to match brain cortex, limbs, skin, spinal cord and mucosal tissues.

The supporting software is split into independent LSI measurement module and LIA post-analysis module. Real-time blood flow color images and perfusion curves are captured and saved during experiments; all stored datasets can be repeatedly processed offline for advanced quantitative analysis. Class 1 safe 780nm laser meets global biomedical lab safety standards, perfectly matching preclinical neuroscience, ischemia, vascular pharmacology and microcirculation research workflows.

Specification	Parameter Value
Full System Name	OMEGAZONE OZ-EX1 2D Laser Blood Flow Imager
Imaging Principle	Laser Speckle Contrast Imaging (LSCI)
Laser Parameter	780nm wavelength, ≤70mW, Class 1 safety laser
Signal Capture Sensor	USB-powered CMOS camera, 8-bit signal output
Imaging Modes & Resolution	1. Hi-Res: 1fps, 639×480 2. Hi-Speed:15fps,213×160 3. HS-AVG: averaged frames,213×160
Adjustable Imaging FOV	Min 8mm×6mm; Max 108mm×80mm (interchangeable lenses)
Power for Laser & Camera	USB 5V, 0.4A
Main Host Dimension (W×H×D)	380 × 40 × 250 mm
Main Host Weight	3 kg
Support Stand Size	Height 30cm, Arm length 15cm; Weight 1.5 kg
CMOS Camera Dimension	16 × 6 × 15 cm; Weight ~0.5 kg
Supporting Computer OS	Windows 11
Minimum PC Configuration	Intel iCore / AMD Ryzen CPU, ≥8GB RAM, 14–16 inch 1920×1080 screen
Software Suite	LSI (Real-time Measurement) + LIA (Offline Quantitative Analysis)
ROI Function	LSI supports 2 ROIs; LIA supports up to 8 storable ROIs
Data Export Format	CSV file compatible with Excel
Core Measurement Index	FLOW value (average perfusion of selected ROI regions)
Key Optical Design	Built-in polarization filter & laser wavelength bandpass filter

Product Feature

Hardware Advantages

Ultra-compact integrated laser & CMOS camera, suitable for small fume hoods and confined experimental stations
USB 5V power supply for laser and camera; only laptop requires mains power, simplified wiring layout
Built-in dual filters: polarization filter blocks surface reflective noise + wavelength filter for 780nm laser signal screening, effectively eliminating measurement artifacts
Class 1 safety 780nm laser (≤70mW), no laser hazard to animals and operators
Interchangeable lens design, adjustable imaging FOV: 8×6 mm ~ 108×80 mm
Complete adjustable metal support stand for flexible height and angle positioning of camera module
Lightweight main host and camera, easy to transport between experimental rooms

LSI Real-Time Measurement Software Functions

Auto/Manual image gain adjustment for flexible brightness calibration
Optical zero function to suppress ambient light interference during measurement
Dual color rendering modes: Standard / Enhanced for different visualization demands
Event marker tool to tag timestamps on blood flow images and real-time perfusion curves
Three switchable imaging modes for diverse research demands
- Hi-Res: 1 frame/sec, 639×480 high resolution for fine tissue perfusion details
- Hi-Speed: 15 frames/sec, 213×160 for capturing rapid dynamic blood flow fluctuation
- HS-AVG: Averaged high-speed frames at 213×160 resolution for stable low-noise imaging

LIA Offline Analysis Software Functions

Dual display color modes: Grayscale / Blue-Red perfusion heatmap
Difference comparison function to visualize perfusion increase/decrease vs reference baseline images
Zero-cut calculation to exclude zero-value pixels and output true average blood flow of ROI regions
ROI storage: Save & recall up to 8 independent region-of-interest areas for batch analysis
Export average FLOW blood flow values of ROIs as CSV files for Excel statistical processing
Histogram display of perfusion value distribution across imaging area
Animation playback with adjustable frame rate for reviewing recorded continuous imaging sequences
Quick navigation tools: single frame back/forward, multi-frame skip jump, one-click restore factory settings