Labodorf SWL-15 Trans Epidermal Water Loss Analyzer | Japan Origin TEWL Meter-Labcan Scientific

Product Description

In order to maintain the skin in good condition, try to avoid the factors that lead to the increase of TEWL, such as direct sunlight, bad weather and temperature, clothes that are easy to cause itching and so on. In addition, you can apply sunscreen, and use a gentle and less abrasive body wash when taking a shower. Of course, using moisturizing cream can also help to keep your skin in a good moisture Human skin normally loses a small amount of water. Under certain conditions, such as acne, skin inflammation, dehydration etc., transepidermal water loss is much higher than normal. The TEWL value (Trans Epidermal Water Loss) is the main parameter for non-invasive and objective assessing of the skin barrier function, and TEWL measurement is an important method for the study ofskin irritation caused by various physical and chemical influences. Typical applications are the evaluation of the efficacy test of various cosmetic products, such as: moisturizing, anti-acne,repair, snoothing, exfoliation etc ., the development of formulations for skin care products, R&D of topical drugs for skin diseases, and so on. state.The accuracy of TEWL measurement is affected by environmental factors, such as temperature and humidity, airflow and internal factors of human body. Therefore, the measurement of TEWL must be carried out under standardized conditions.

VAPOSCAN AS-VT100 is a professional closed-chamber portable TEWL analyzer developed for objective, non-invasive evaluation of human & animal skin barrier function, fully compliant with EEMCO, FDA and OECD skin testing standards.Transepidermal Water Loss (TEWL) is the core quantitative indicator of skin barrier integrity: damaged stratum corneum caused by inflammation, dryness, acne or irritation will sharply raise TEWL value. This tester is the standard lab equipment to verify cosmetic moisturizing, soothing, anti-irritation, barrier repair efficacy, as well as evaluate skin penetration safety of topical pharmaceuticals.Different from open-type TEWL devices vulnerable to ambient wind, AS-VT100 adopts fully enclosed detection chamber. When the probe contacts skin surface, the internal sensor records real-time absolute humidity change within 10 seconds, automatically calculates standardized TEWL value (g/m²/h). Built-in high-speed CPU eliminates manual operation errors, automatically judges stable measurement endpoint to guarantee repeatable experimental data.

The instrument supports interchangeable multi-size probes to cover all test sites from large forearm skin to tiny lip, periocular, scalp and mouse skin. Dual power design enables flexible use in constant-temperature-humidity cosmetic labs, hospital dermatology departments, university pharmacology labs and toxicology testing institutions. All test data can be transmitted to PC via RS232 serial port; matched DAQ software supports batch data sorting, curve plotting and formal experiment report export.Widely recognized in cosmetic claim substantiation, transdermal drug IVPT testing, chronic skin disease model research and EU REACH raw material skin irritation risk assessment, AS-VT100 provides traceable, comparable quantitative data for global skin pharmacology & cosmetic efficacy laboratories.

Closed Chamber Measuring Technology: Fully shield external airflow turbulence, stable TEWL data without environment interference, meets EEMCO official test guidelines.
Ultra-fast Detection: Single measurement completes within 5–14 seconds, automatic identification of start & stop measurement timing by built-in high-performance CPU.
Wide Measurement Range & High Precision: TEWL range –100 ~ 300 g/m²/h, 0.1 g/m²/h ultra-fine resolution, capture both mild & severe skin water loss accurately.
Replaceable Multi-aperture Probes: Standard 12mm probe, optional 10/8/6/4mm probes, adapt to cheek, eye area, lip, scalp, nail, forearm and tiny animal skin sites.
Dual Power Supply Mode: Support 9V battery & AC adapter, lightweight 200g body for field portable testing or fixed lab workstation use.
Complete Real-time Data Monitoring: Simultaneously display TEWL value, temperature, humidity & SD variation; RS232 data export + optional DAQ analysis software for lab report archiving.
Non-invasive Safe Test: Gentle probe contact, no skin damage, suitable for human volunteer clinical trials & animal dermatitis model research.

Product Parameters

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Industry Standards and Guidances

1. Berardesca E, Loden M, Serup J, Masson P, Rodrigues LM. The revised EEMCO guidance for the in

vivo measurement of water in the skin. Skin Res Technol. 2018 Aug; 24(3):351-358.

2. Guideline on quality of transdermal patches, October 2014，EMA

3. In Vitro Permeation Test Studies for Topical Drug Products Submitted in ANDAs Guidance for

Industry. October 2022 ，FDA

4. Skin Absorption: in vitro Method，April 2004,OECD

Product Feature

Japan Precision Engineering : Utilizes advanced micro-humidity and temperature sensors for ultra-low noise, high repeatability, and fast response times.
Non-Invasive & Contact Safety : Designed for completely non-destructive, painless measurement on various human skin areas (face, forearms, etc.).

Ergonomic Handheld Probe : Light contact pressure probe design minimizes micro-climate disruption on the skin surface during testing.

Cosmetic Efficacy Claim Support: Provides quantitative TEWL data satisfying international standard protocols for moisturizing and repair claims.

User-Friendly Data Analysis : Connects seamlessly with analysis software for real-time data logging, curve tracking, and report generation.

•Measure within 14 seconds by gently pressing the opening of the measuring probe against the skin and pressing the button to obtain the value.
•The closed-volume measurement method is not affected by air turbulence or airflow.
•With a wide measurement range, precise readings can be obtained for both trace amounts and significant moisture loss through a high-precision digital analog sensor.
•Equipped with a high-performance CPU that monitors humidity and temperature inside the chamber in real time. It
automatically determines the optimal measurement start time and identifies the measurement end time.
•The AC adapter and battery can be used interchangeably, fully leveraging the advantages of a portable device.
•The diameter of the opening is 12 mm (standard configuration), with optional options of 6 mm or 4 mm. By using measurement probes of different diameters, the skin barrier in various areas such as the face, forearm, lips, periorbital region, scalp, and nails can be studied.

VAPOSCAN AS-VT100 portable TEWL analyzer adopts closed chamber technology, anti-airflow interference, multi-size optional probes, RS232 data output. Comply with EEMCO & FDA standards for cosmetic efficacy test, topical drug R&D and dermatology research.